Blog
Educational material, comparison studies and publications on SPR and other related techniques for researchers.
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Hot New App Note: Temperature Dependent Binding Kinetics of Protein-Protein Interactions Using OpenSPR™
Is temperature dependence important for your binding interactions? In our hot new application note as we demonstrate how OpenSPR’s Temperature Control Add-On can be used to analyze the effect of temperature on the kinetics and affinity of a protein-protein interaction. Surface plasmon resonance (SPR) can be used to analyze all types of interactions including protein-protein, protein-small […]
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Meet the world’s youngest benchtop SPR user: 17-Year-Old Eric Wang
As life science researchers, we all understand the importance of obtaining reliable, consistent binding kinetics for biomolecular interactions. Researchers also know that using SPR to measure these kinetics is the gold-standard technique. However, many researchers face a huge barrier when considering SPR for their projects – SPR has traditionally required a huge learning curve, and […]
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Mastering the Art of Regeneration – The Key to SPR Success
Using surface plasmon resonance to get high-quality binding kinetics is definitely rewarding, but the biggest challenge is often finding the right experimental conditions to get optimal binding kinetics. One of the most important steps to consider is the regeneration step, or more specifically, the regeneration buffer. The regeneration buffer is used to disrupt or reverse the binding between the ligand and analyte, and is often an essential step to getting good kinetics. This can be a tricky task, so we hope that these tips will help you rock your regen! We’ll be going over the principles of regeneration, when to use it, how to optimize it according to your ligand and analyte, and what the resulting benefits are if you execute the steps correctly.
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Nicoya Hires Senior Sales and Marketing Executive Jim Harp to Drive Global Expansion
Nicoya recently hired Jim Harp to serve as their VP of Business Development. Nicoya is looking to fuel the growth of OpenSPR through expanding internationally via channel partners and strategic OEM partners, and needed someone experienced and dedicated to that role. Jim is the perfect fit – a California native with deep industry sales experience and a fondness for KW. In addition, he’s a super cool guy – in his spare time, Jim spends his weekends motocross racing, desert dirt biking, surfing and coaching hockey. We interviewed Jim to get to know him better and get an idea of why he joined Nicoya. Jim Harp Senior VP of Business Development Jim has over 20 years of experience in various senior management positions in sales, marketing, and channel development. He has helped scale a number of products and businesses globally by establishing and managing distribution partners and strategic OEM relationships. He has extensive experience working in optics and photonics for the medical diagnostic and analytical instrumentation market while with companies like PerkinElmer and Semrock (now Idex).
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Why Every Biochemistry Teaching Lab Needs SPR Technology
SPR is a gold standard technique used in the biotechnology industry to measure binding kinetics and molecular interactions. This data is of critical importance – it helps scientists understand how diseases work, helps them to design the next blockbuster drug, and helps ensure biosimilars meet FDA regulations, just to name a few examples. So why isn’t SPR being taught to young scientists in college and university, alongside other standard techniques like western blot, ELISA, or HPLC? One big reason is the cost, and the other is the complexity. Luckily, OpenSPR solves these problems, and is a perfect addition to help modernize teaching labs, bringing them into the 21st century and ensuring your students have the skills they need to be competitive and successful.
In this blog post, we will highlight why teaching labs need to adopt SPR and how they can do this effectively and within budget with Nicoya’s OpenSPR. -
Automated Surface Plasmon Resonance Levels the Playing Field in Protein Science
On January 20, we announced our newest product, OpenSPR-XT – a fully automated molecular analysis instrument based on the highly successful OpenSPR instrument. The release of OpenSPR-XT will provide life sciences researchers from academia to industry with a high throughput SPR solution that is affordable for every lab. The OpenSPR line of surface plasmon resonance instruments […]
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Our Top 5 Biosensor Enabled Digital Health Tech Gadgets from CES 2016
Biotech is changing the world, and everyone knows it. There is nothing more exciting than hearing about the newest biotech apps and gadgets that will help us maintain our health for years to come. Many people have been talking about the huge number of digital health products at CES this year. So we decided to […]
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6 Advantages of Surface Plasmon Resonance Technology
Surface plasmon resonance (SPR) has been around for more than 20 years, yet many researchers still rely on outdated techniques to characterize biological interactions because of the cost and complexity of SPR analysis. Now that SPR technology is becoming more affordable and accessible, it is important for researchers to understand the value that SPR data […]
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Discover Why RNA Interactions and Binding Kinetics Matter
Using SPR for RNA Binding Kinetics at Rustbelt Meeting 2015 We recently attended the wonderful Rustbelt RNA meeting in Sandusky, Ohio organized by Blanton Tolbert and Charles Hoogstraten. The yearly meeting attracts top-quality participants from prestigious schools from the Midwestern and Mid-Atlantic regions in the United states and Canada. It was refreshing to chat with […]
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SPR Tips: 3 Ways To Limit Mass Transfer Effects In Kinetic Data
In surface plasmon resonance, the reactant in a solution must first diffuse from the bulk to the surface to interact with the immobilized ligand. If the diffusion rate is slower than the association rate, mass transfer effects can be observed in the data. Mass transfer limitations are most common for fast binding reactions, as diffusion […]
