Publications Archive - Nicoya - Improving Human Life by Helping Scientists Succeed https://nicoyalife.com Publication quality binding kinetics & affinity data on your benchtop. Mon, 26 Jun 2023 15:02:53 +0000 en-US hourly 1 https://wordpress.org/?v=5.8.8 https://nicoyalife.com/wp-content/uploads/2019/02/Nicoya-Favicon-150x150.png Publications Archive - Nicoya - Improving Human Life by Helping Scientists Succeed https://nicoyalife.com 32 32 Maturation of the malarial phosphatidylserine decarboxylase is mediated by high affinity binding to anionic phospholipids https://nicoyalife.com/publications/maturation-of-the-malarial-phosphatidylserine-decarboxylase-is-mediated-by-high-affinity-binding-to-anionic-phospholipids/ Tue, 20 Jun 2023 20:03:45 +0000 https://nicoyalife.com/?post_type=publications&p=20363 Jae-Yeon et al. Maturation of the malarial phosphatidylserine decarboxylase is mediated by high affinity binding to anionic phospholipids. Journal of Biological Chemistry, 2023. 299, 5. https://doi.org/10.1016/j.jbc.2023.104659 Keywords: phosphatidylserine decarboxylase; phosphatidylserine; phosphatidylethanolamine; proenzyme processing; enzyme regulation; anionic phospholipid; phosphatidylglycerol; phosphatidic acid; cardiolipin; phosphatidylcholine; liposome; solid phase binding; surface plasmon resonance Abstract: Decarboxylation of phosphatidylserine (PS) to form […]

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]]> Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022 https://nicoyalife.com/publications/application-of-the-nicoya-openspr-to-studies-of-biomolecular-binding-a-review-of-the-literature-from-2016-to-2022/ Mon, 29 May 2023 19:00:16 +0000 https://nicoyalife.com/?post_type=publications&p=20315 Hanson, E.K.; Whelan, R.J. Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022. Sensors. 2023, 23, 4831. https://doi.org/10.3390/s23104831 Keywords: localized surface plasmon resonance; Nicoya Life Sciences; OpenSPR; binding affinity Abstract: The Nicoya OpenSPR is a benchtop surface plasmon resonance (SPR) instrument. As with other optical biosensor instruments, it is suitable for the […]

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]]> Dysregulated naive B cells and de novo autoreactivity in severe COVID-19 https://nicoyalife.com/publications/dysregulated-naive-b-cells-and-de-novo-autoreactivity-in-severe-covid-19/ Fri, 18 Nov 2022 19:55:04 +0000 https://nicoyalife.com/?post_type=publications&p=19526 Woodruff, M.C., Ramonell, R.P., Haddad, N.S. et al. Dysregulated naive B cells and de novo autoreactivity in severe COVID-19. Nature 611, 139–147 (2022). https://doi.org/10.1038/s41586-022-05273-0 Interaction Type: antibody-antigen Abstract: Severe SARS-CoV-2 infection1 has been associated with highly inflammatory immune activation since the earliest days of the COVID-19 pandemic2,3,4,5. More recently, these responses have been associated with the emergence of self-reactive antibodies […]

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]]> Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent https://nicoyalife.com/publications/heterophilic-and-homophilic-cadherin-interactions-in-intestinal-intermicrovillar-links-are-species-dependent/ Mon, 06 Dec 2021 17:10:00 +0000 https://nicoyalife.com/?post_type=publications&p=18847 Gray, M. E.; Johnson, Z. R.; Modak, D.; Tamilselvan, E.; Tyska, M. J.; Sotomayor, M. Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent. PLoS Biol 2021, 19 (12), e3001463. DOI: 10.1371/journal.pbio.3001463. Interaction Type: protein-protein Abstract: Enterocytes are specialized epithelial cells lining the luminal surface of the small intestine that build densely packed arrays of microvilli […]

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]]> A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue https://nicoyalife.com/publications/a-strategy-to-detect-emerging-non-delta-sars-cov-2-variants-with-a-monoclonal-antibody-specific-for-the-n501-spike-residue/ Fri, 12 Nov 2021 17:12:00 +0000 https://nicoyalife.com/?post_type=publications&p=18851 Puligedda, R. D.; Al-Saleem, F. H.; Wirblich, C.; Kattala, C. D.; Jović, M.; Geiszler, L.; Devabhaktuni, H.; Feuerstein, G. Z.; Schnell, M. J.; Sack, M.; et al. A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue. Diagnostics 2021, 11 (11), 2092. Interaction Type: Protein-antibody Abstract: Efforts to control SARS-CoV-2 have […]

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]]> Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anti-cancer activities in lung adenocarcinoma. https://nicoyalife.com/publications/engineered-variants-of-the-ras-effector-protein-rassf5-nore1a-promote-anti-cancer-activities-in-lung-adenocarcinoma/ Fri, 05 Nov 2021 15:44:50 +0000 https://nicoyalife.com/?post_type=publications&p=18555 Singh, A.; Erijman, A.; Noronha, A.; Kumar, H.; Peleg, Y.; Yarden, Y.; Shifman, J. M. Interaction Type: Protein-protein Abstract: Within the superfamily of small GTPases, Ras appears to be the master regulator of such processes as cell cycle progression, cell division, and apoptosis. Several oncogenic Ras mutations at amino acid positions 12, 13, and 61 […]

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]]> Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding https://nicoyalife.com/publications/distinct-mutations-in-importin-%ce%b2-family-nucleocytoplasmic-transport-receptors/ Sun, 01 Aug 2021 16:58:00 +0000 https://nicoyalife.com/?post_type=publications&p=17698 Kimura, M.; Imai, K.; Morinaka, Y.; Hosono-Sakuma, Y.; Horton, P.; Imamoto, N., Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding. Sci Rep 2021, 11 (1), 15649. Interaction Type: Protein-protein Abstract: Importin-(Imp)β family nucleocytoplasmic transport receptors (NTRs) are supposed to bind to their cargoes through interaction between a confined […]

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]]> Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus https://nicoyalife.com/publications/direct-interaction-of-dna-repair-protein-tyrosyl-dna-phosphodiesterase-1-and-the-dna-ligase-iii-catalytic-domain-is-regulated-by-phosphorylation-of-its-flexible-n-terminus/ Fri, 25 Jun 2021 14:47:00 +0000 https://nicoyalife.com/?post_type=publications&p=17004 Rashid, I.; Hammel, M.; Sverzhinsky, A.; Tsai, M. S.; Pascal, J. M.; Tainer, J. A.; Tomkinson, A. E., Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus. J Biol Chem 2021, 100921. Interaction Type: Protein-protein Abstract: Tyrosyl DNA phosphodiesterase […]

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]]> Peptidomimetic-based antibody surrogate for HER2 https://nicoyalife.com/publications/peptidomimetic-based-antibody-surrogate-for-her2/ Sat, 01 May 2021 14:35:00 +0000 https://nicoyalife.com/?post_type=publications&p=17001 Zheng, M.; Chunpu, L.; Zhou, M.; Jia, R.; She, F.; Wei, L.; Cheng, F.; Li, Q.; Cai, J.; Wang, Y., Peptidomimetic-based antibody surrogate for HER2. Acta Pharmaceutica Sinica B 2021. Interaction Type: Protein-peptide Abstract: Inhibition of human epidermal growth factor receptor 2 mediated cell signaling pathway is an important therapeutic strategy for HER2-positive cancers. Although monoclonal antibodies are currently […]

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]]> Astemizole as a drug to inhibit the effect of SARS-COV-2 in vitro https://nicoyalife.com/publications/astemizole-as-a-drug-to-inhibit-the-effect-of-sars-cov-2-in-vitro/ Thu, 29 Apr 2021 17:02:58 +0000 https://nicoyalife.com/?post_type=publications&p=16979 Wang, X.; Lu, J.; Ge, S.; Hou, Y.; Hu, T.; Lv, Y.; Wang, C.; He, H., Astemizole as a drug to inhibit the effect of SARS-COV-2 in vitro. Microb Pathog 2021, 104929. Interaction Type: Protein-small molecule Abstract: Since the beginning of December 2019, a novel Coronavirus severe respiratory disease, caused by Severe Acute Respiratory Syndrome […]

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